SR9009 mbadamba 100 mbadamba / karama

Aha ngwaahịa:SR9009

Ọdịiche: 10 mg / pill 100 ọgwụ / karama

Ahịa: $80 / karama

MOQ: 1 karama

Ụlọ nyocha: LianFu Bio

Nkọwapụta ngwaahịa

SR9009, REV-ERBagonist, na-abawanye mmechi nke mkpụrụ ndụ ihe nketa nke REV-ERBα/ERBβ na-achịkwa (IC50: 670/800 nM).Site na ịgbalite REV-ERB, SR9009 nwere ike ibelata ọrụ locomotor circadian n'oge ọchịchịrị wee gbanwee usoro ngosipụta nke mkpụrụ ndụ ihe nketa elekere na hypothalami nke ụmụ oke.Usoro okirikiri nke ngosipụta nke ọtụtụ mkpụrụ ndụ ihe nketa metabolic na imeju, akwara skeletal, na anụ ahụ adipose ka agbanwekwara na ụmụ oke ekpughere na SR9009, na-ebute mmụba ike.

SR9009 (100 mg / kg, ip, bid, maka ụbọchị 30) nwere ikebelata oke abụbana nke pụtara ìhèmelite dyslipidemianahyperglycemia.