China Supply Sarms Raw Sr9009 Stenabolic API
REV-ERBα na REV-ERBβ ndị na-anabata ihe nuklia bụ ndị na-emegharị ihe na-eme ka ọ bụrụ ihe na-ahazi usoro circadian na usoro metabolic n'ụzọ dabere na heme.SR9009 bụ agonist REV-ERB nke na-abawanye mmechi nke mkpụrụ ndụ ihe nketa nke REV-ERBα na REV-ERBβ na-achịkwa ụkpụrụ IC50 nke 670 na 800 nM, n'otu n'otu.1Site na ịgbalite REV-ERB, SR9009 egosila na ọ na-ebelata ọrụ locomotor circadian n'oge oge ọchịchịrị yana ịgbanwe usoro okwu nke mkpụrụ ndụ ihe nketa elekere na hypothalami nke ụmụ oke.1A na-egosikwa na a ga-agbanwekwa usoro nke circadian nke mkpụrụ ndụ ihe nketa metabolic na imeju, akwara ọkpụkpụ na anụ ahụ adipose ka ọ gbanwere na ụmụ oke ekpughere SR9009, na-ebute mmụba ume ike.1 oke oke ibu na-eri nri na-emeso ya na 100 mg/kg. SR9009 (ip ugboro abụọ n'ụbọchị maka ụbọchị 30) ka akọọrọ ka ọ gosipụta oke abụba belatara yana mmụba nke dyslipidemia na hyperglycemia.1
Ịdọ aka ná ntị Ngwaahịa a abụghị maka mmadụ ma ọ bụ ọgwụgwọ anụmanụ.